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Model No. : | S007.R01000 |
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Brand Name : | OHI |
Test Method : | HPLC |
Changsha, Hunan, China
Product description
St John's Wort Extract is extract from John's Wort leaf and root (Hypericum perforatum) , Hypericum perforatum is also known as perforate St John's-wort, common Saint John's wort and St John's wort. The main active ingredient of St John's Wort Extract is Hypericin, Hypericin is believed to act as an antibiotic, antiviraland non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.
Hypericum perforatum, known as perforate St John's-wort, common Saint John's wort and St John's wort, is a flowering plant in the family Hypericaceae. The common name "St John's wort" may be used to refer to any species of the genus Hypericum. Therefore, Hypericum perforatum is sometimes called "common St John's wort" or "perforate St John's wort" in order to differentiate it. It is a medicinal herb with antidepressant activity and potent anti-inflammatory properties as an arachidonate 5-lipoxygenase inhibitor and COX-1 inhibitor.
Hypericin is a naphthodianthrone, a red-colored anthraquinone-derivative, which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort).Hypericin is believed to act as an antibiotic, antiviraland non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.
It was initially believed that the anti-depressant pharmacological activity of hypericin was due to inhibition of monoamine oxidase enzyme. The crude extract of Hypericum is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors. This points in the direction that other constituents are responsible for the MAOI effect. The current belief is that the mechanism of antidepressant activity is due to the inhibition of reuptake of certain neurotransmitters.
This can be used in food industry,cosmetic industry,medical industry.
It has been used for centuries to calm the nerves and treat depression. It also has been used to dress wounds, heal deep cuts, smooth bums and ease the pain of neuralgias. Taken internally, it has been used forulcers and gastritis. An infusion of the herb has also been used as an expectorant for bronchitis, a diuretic for the kidneys and an easing agent for menstrual cramps.
Changsha, Hunan, China
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