Optogenetics is a neuromodulation technique employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue to precisely measure the effects of those manipulations in real-time. Changchun New Industries (CNI) offers fiber-coupled laser as the stimulation light source for the optogenetics research, which provides a controlled wavelength and pulsing modulation option, and having fiber optics attached to the laser module allows for a convenient method of delivering the light to a selected target site. CNI's blue, yellow, and green laser modules are currently being used in many leading laboratories, also we can provide the below wavelengths with options such as enhanced power stability, low noise amplitude, power adjustment and controllable pulse frequency/duty cycle.
Features CNI provided high reliability lasers All the necessary accessories can be provided Easy to install and maintain Customized solution can be provided upon request SPECIFICATIONS:
Wavelength (nm) | 635±5 |
Output power (mW) | >1, 10, 100, … , 200 |
Transverse mode | Near TEM00 |
Operating mode | CW |
Power stability (rms, over 4 hours) | <1%, <3%, <5% |
Warm-up time (minutes) | <5 |
Beam divergence, full angle (mrad) | <1.0 |
Dimensions of beam at the aperture (mm) | ~3. 0 |
Beam height from base plate (mm) | 24. 8 |
Polarization ratio | >50:1 |
Pointing stability after warm-up (mrad) | <0.05 |
Operating temperature (℃) | 10~35 |
Power supply (90-264VAC or 5VDC) | PSU-III-LED | PSU-III-FDA |
Modulation option | TTL/Analog 1Hz-5KHz, 1Hz-10KHz, 1Hz-30KHz, and TTL on/off |
Expected lifetime (hours) | 10000 |
Warranty | 1 year |
Laser Head
PSU-III-LED Power supply
PSU-III-FDA Power supply
Accessories: Fiber Patch Cables Fiber Optic Cannula and mating sleeve
SM Fiber, PM Fiber, MM Fiber(50-400µm) Implantable Fiber Optic Cannula Wavelength range:320nm-2200nm Outer Diameter of cannula:Φ1.25mm,Φ2.5m Fiber length:1m, 2m, others on request Cannula: Ceramic, stainless steel Rotary Joint Acoustic-Optical-Modulator
Prevents Fiber Damage from Specimen Movement Modulation repetition rate(0-4MHz) Connector:FC or SMA905 Diffraction Efficiency:>75% Wavelength Range:320nm-2200nm Wavelength range:450nm-850nm( others optional) Beam Shutter Power Meter
Delay from the electrical signal:4ms Supplied with real time monitor software Repetition Rate:0-10Hz available data storage Rising time and fall time:250µs Wavelength Range:0.19-25um Some of our most popular lasers which are currently being used for optogenetics research are listed below: 532 nm 561 nm 589 nm 593.5 nm Research achievements of CNI laser for Optogenetics from customers (1) Optogenetic stimulation of a hippocampal engram activates fear memory recall
(Nature, 484(7394): 381–385. doi:10.1038/nature11028) (CNI-473nm) (2) Ultrahigh accuracy imaging modality for super-localization microscopy
(Nature Methods, VOL.10,2013,335) (CNI-635nm and 488nm) (3) Remote Optogenetic Activation and Sensitization of Pain Pathways in Freely Moving Mice
(The Journal of Neuroscience, 2013•33(47):18631–18640) (CNI-589nm) (4) Optogenetic Evidence That Pallidal Projections, Not Nigral Projections, from the Nucleus Accumbens Core Are Necessary for Reinstating Cocaine Seeking
(The Journal of Neuroscience, 2013•33(34):13654–13662) (CNI-561nm) Company Information Changchun New Industries (CNI) founded in 1996, located in Changchun, CHINA, is a leading manufacturer of solid-state and diode laser systems. Our products include green laser, blue laser, yellow laser, red laser, RGB laser, infrared laser, UV laser, single longitudinal mode laser and Q-switched laser systems. CNI lasers are featured with high performance, low cost and excellent laser beam quality, which are specifically designed for OEM, scientific, industrial and instrumentation use. In addition, CNI lasers are ISO-9001, FDA, CE, RoHS and JQA certified. CNI also provides laser components and accessories, we aim to offer customers complete laser solutions for all solid state lasers, diode lasers, laser marking system with our most convenient and rapid service.
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