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Protein A Affinity Chromatography Resins UniMab
| Model No. : | UniMab 50HC |
|---|---|
| Pore Size : | 1000 |
Product description
Product Description
UniMabTM protein A affinity resins are made with highly crosslinked polymethacrylate matrices of monodisperse particle size and proprietary, engineered protein A ligand for enhanced chemical stability.
· Monodisperse matrices of high mechanic strength allows fast flow for improved process productivity.
· Enhanced alkaline stability enables efficient cleaning and sanitization using 0.1–0.5 M NaOH for improved resin lifetime, process economy, bioburden control.
UniMabTM 50 is NanoMicro’s first generation protein A resin of robust performance. UniMabTM 50HC has improved dynamic binding capacity.
Product Attributes
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UniMabTM 50 |
UniMabTM 50HC |
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Matrix |
Monodisperse, highly crosslinked polymethacrylate |
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Ligand |
Engineered Protein A |
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Ligand coupling chemistry |
Expoxy |
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Particle Size |
50 μm |
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IgG Dynamic Binding Capacity（5 min residence time） |
40 mg/mL |
50 mg/mL |
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Protein A leachate |
< 10 ng/mL |
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Endotoxin |
< 5 EU/mL |
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Microbial contamination |
< 100 cfu/mL |
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Operation pressure |
≤ 0.3 MPa |
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CIP conditions |
0.1-0.5 M NaOH |
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Storage |
2˚C to 8˚C, 20% ethanol |
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Chemical stability |
Stable to commonly used aqueous buffers in protein A chromatography |
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