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Product Overviews What's Mucuna Pruriens? Mucuna Pruriens is a tropical legume known as velvet bean  (Ci mao li dou in Chinese), native to Africa and Asia and widely naturalized. The plant is notorious for the extreme itchiness it produces on contact, particularly with the young foliage and the seed pods. It has value in agricultural and horticultural use and has a range of medicinal properties. Mucuna pruriens seed pod M. pruriens  seed contains L-DOPA, a precursor to the neurotransmitter dopamine and formulations of the seed powder have been studied for the management and treatment of Parkinson's disease. In large amounts (e.g. 30 g dose), it has been shown to be as effective as pure levodopa/carbidopa in the treatment of Parkinson's disease, but no data on long-term efficacy and tolerability are available. Mucuna pruriens seeds of two different colors What is Levodopa? L-Dopa is an amino acid and a hormone that is made naturally by a number of plants and animals. In humans, it is created via biosynthesis from the amino acid L-Tyrosine. It is a precursor to several important and powerful neurotransmitters which include Dopamine, Norepinephrine (Noradrenaline) and Epinephrine (Adrenaline). These are collectively known as catecholamines and they play a role in the stimulation and arousal systems in your brain. In its pure form,  L-Dopa is considered to be a psychoactive chemical, and can also be used for the treatment of Parkinson’s Disease and a number of other conditions related to lowered levels of the above neurotransmitters (especially Dopamine). As a nootropic,  L-Dopa is used to combat depression and anxiety while enhancing mood and improving the ability to concentrate and focus.    Levodo- pa (L-Dopa), which crosses the blood-brain bar- rier and replaces the loss of dopamine in the brain. One of the main drawbacks of the ad- ministration of L-Dopa is its short half-life, due to the presence of enzymes, such as the amino acid decarboxylase (AADC), able to rapidly me- tabolize L-Dopa. For this reason the intake of L-Dopa takes always place together with an AADC inhibitor such as carbidopa.  Levodopa‘s Effects? Levodopa is used therapeutically in Parkinson’s disease patients since it is a precursor for dopamine, an inhibitor of tyrosine hydroxylase. Levodopa therapy increases brain dopamine levels, increases dopamine turnover and prolongs the lives of patients. Levodopa greatly improves the quality of life and length of life in Parkinson’s disease patient. The main function of L-Dopa is as a precursor to several different neurotransmitters, especially Dopamine. The Dopamine chemical cannot itself cross over the blood-brain barrier and must be synthesized in the brain. However, L-Dopa can penetrate this barrier and leads to increased levels of this pleasure-inducing hormone. L-Dopa is converted into Dopamine by the DOPA decarboxylase enzyme, also known as aromatic  L-amino acid decarboxylase. Another necessary component of this process is Vitamin B6 (Pyridoxal phosphate) which is often stacked with L-Dopa supplements for increased conversion efficiency.  Once this action is complete,  L-Dopa causes a stimulatory effect on the Central Nervous System. The hypothalamus area of the brain,  along with the pituitary gland, release increased levels of growth hormone (HGH). It has also been shown to increase the levels and activities of the adrenergic hormones Norepinephrine and Epinephrine. The combined presence of these increased levels of hormones and neurotransmitters are responsible for a number of beneficial effects like regulating motor control, sex drive, immune function, fat loss (and gain), lean muscle growth, bone density, energy levels, and even sleep cycles. L-Dopa helps to remove toxins and poisons from the body, especially the brain, including free radicals and other particles which have been damage due to oxidation. Another benefit of this nootropic is that it raises plasma HGH levels which can contribute to improved whole body health as well as reduce signs of aging in elderly individuals.  L-Dopa is also effective at increasing testosterone production. This leads to enhanced ability to increase muscle mass and to lose weight (not to mention maintain a lower weight). This is an excellent supplement for anyone engaged in weight or strength training.  Application: 1. Levodopa can be applied in pharmaceutical field. 2. Levodopa can be applied in health supplement. 3. Levodopa can be applie in functional food additive. 4. Levodopa can be applie in cosmetics and personal care products.   Packing & Storage

Shelf Life	2 years if sealed and store away from direct sun light
Packing	25kgs/drum,double plastic-bag inside, aluminum foil bag or fiber drum outside.
Storage	Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat

  Company Information Hunan Zhengdi Biological Resources Development Co., Ltd. is a GMP manufacturer and we have provided  high quality product and service to  the plant extract industry of dietary supplements, functional foods/beverage,  and pharmaceutical for more than 10 years. We  concentrates on the high-efficient comprehensive development of plant resources and their deep-processing products. We are a manufacturer, a high-tech enterprise with enormous experience in research and development, as well as abundant plant resources.  Our Management team has abundant pharmaceutical professional background, and main supervisory technical staffs have application and registration experiences of medical products and health-related products for ten years and can accurately grasp the requirements of policies, regulations and technical principles of medical products and health- related products. Focusing on R&D and keep improving We have made a breakthrough on processing technology in order to meet the limits of microorganism and heavy metal content. We have experiences on R&D of medicine and health food for over 10 years, and our advantage are research on preparation technology, quality standard and study on general pharmacology & toxicology. Outstanding advantages on controlling the resources We have own planting base of herbal medicines and cooperate with professional herbal medicine cultivation institutions. The cultivation is strictly according to the requirements of Chinese GAP standard. To ensure the raw material quality, harvest season, field processing, storage and transportation are also strictly controlled. Outstanding achievements on quality management Our company has built the GMP plant completely complying with Good Manufacture Practice in Hunan Zhanda Taikang Pharmaceutical Co., Ltd. and has the relevant Chinese drug GMP certificate. Production is strictly conducted according to Good Manufacture Practice. All the procedures are regulated by relevant GMP documents, from the purchase of raw material to sales of the finished product, to ensure the traceability of the whole production process in order to guarantee the product quality.    Our Services A) ZD Biological plant extract is 100% extracted from natural aged root, very safe and more bioactive. B) ZD Biological plant  extract has the high purity to meet your body needs. C) ZD Biological plant  extract almost have no unpleasant taste compare to others'. and it can be easier to take by oral. D) ZD Biological offer green and natural plant  extract at a very lower price with a very high and uniform quality. E) More important ---We have a very large output to meet our customers' big and continual orders.   FAQ Q: Why order with Zhengdi? A: Zhengdi is a plant extract GMP manufacturer for nearly 10 years. We can supply special customized  products for you with high quality. The most important is that we can provide technical help for you when  you need to develop a new product. Q: How can i place orders if I’m not familiar with international imports? A: Zhengdi has skillful logistic tea for international shipment operations. We could supply FOB, CIF, door to door service (DDU/DDP terms) for your to some contries, it all depends. Q: Could clients get credit from Zhengdi? A: Zhengdi welcome repeat clients with good payment record to apply for credit. Please contact us for  a credit application form. Q: Could Zhengdi provide us formula design assistance? A: YES, we do. Zhengdi not only supply Botanic/Plant extracts, but also we provide formula design services,  contract manufacturing and natural ingredients applications solutions. Q: What is the Zhengdi products quality control system? A: According to ISO management system, all of our products must be tested during the produce process  with production records. Moreover, all products must be tested again before delivery by Zhengdi lab to be  sure of the product ptency and purity. Zhengdi lab is equipped with HPLC, UV-VIS and related instruments.