Lentinus edodes is the second largest mushroom in the world. It is also one of the most precious edible mushrooms in China. China's first cultivation of Shiitake mushrooms, has been more than 800 years of history. Lentinus edodes is also a famous medicinal fungus in China. Lentinus edodes is a kind of food with the same source of food and medicine. It has high nutritional, medical and health value. Selenium-rich lentinus edodes is a high-protein, low-fat, polysaccharide, a variety of amino acids and a variety of vitamins fungus food, and rich in selenium. Regular consumption of selenium-enriched lentinus edodes can play the role of anti-cancer, anti-oxidation, anti-aging, enhancing human immunity, resisting harmful heavy metals, regulating protein synthesis, enhancing reproductive function, lowering blood pressure, lowering blood lipid and lowering cholesterol, and on Diabetes, tuberculosis, Hepatitis A, neuritis and so on play a therapeutic role.