(2R)-1-{5-Amino-2-[1-(Benzyloxy)-2-Methyl-2-Propanyl]-6-Fluoro-1H-indol-1-yl}-3-(Benzyloxy)-2-Propanol 1294504-67-8

Thera. Category: Cystic Fibrosis Treatment

Cas No.:1294504-67-8

Synonyms:  Tezacaftor Intermediates;(2R)-1-{5-amino-2-[1-(benzyloxy)-2-methyl-2-propanyl]-6-fluoro-1H-indol-1-yl}-3-(benzyloxy)-2-propanol;(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol;VX-661

Molecular Formula:C29H33FN2O3

Molecular Weight:476.582

Purity:99%

Packing: Export worthy packing

Material Safety Data Sheet: Available on request

Usage:Tezacaftor is a drug used for the treatment of cystic fibrosis (CF) in people six years and older, who have a F508del mutation, the most common type of mutation in the CFTR gene.  It is sold as a fixed-dose combination with ivacaftor under the brand name Symdeko.  It was approved by the U.S. FDA in 2018  The combination of elexacaftor, tezacaftor, and ivacaftor is being sold as Trikafta.

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