Sodium iodoacetate Pharmaceutical Intermediates CAS NO 305-

Sodium iodoacetate Pharmaceutical Intermediates CAS NO 305-53-3 98%

Quick Detail:

Name	1,4-bis(2-hydroxyethyl)piperazine	Appearance	White or light yellow crystal
Assay:	≥98.0	Sulphate,%	≤0.01
Loss on drying,%	≤1.0	Heavy metals,%	≤0.001
MP/℃	208 °C	Chloride,%	≤0.01

Description:

> Formula:C2H2INaO2

> Weight: 207.93

> Appearance:White or light yellow crystal

> MP:208 °C

> Storage:2-8℃

> Danger Description:R25 R36/37/38

> Safety Description:S22 S36/37/39 S45

> Danger Symbol:T

> Shelf life:two years

1.Applications:

A.the in vitro stabilization of glucose, lactate and homocysteine in blood

B.preparing medicine for treating malignant tumor

2.Location

A. biology/biochemistry laboratory, pharmaceutical factory, cosmetics factory

Specifications

Assay	≥98.0
MP,℃	208 °C
Loss on drying,%	≤1.0
Sulphate,%	≤0.01
Heavy metals,%	≤0.001
PH(1% aq.)	≤0.01
Chloride,%
Ultraviolet absorbance/280nm(55% aq.)
Dicyandiamide,%
Melamine,%
Iron,ppm
shelf life	two years

Synonyms:

IODOACETIC ACID SODIUM SALT;SODIUM MONOIODOACETATE;SODIUM IODOACETATE;SODIUM IODACETATE SODIUM SALT;Aceticacid,iodo-,sodiumsalt;iodoacetate,sodiumsalt;iodo-aceticacisodiumsalt;usafek-6279;Sodium iodoacetate; Iodoacetic acid sodium salt

Related categories:

Related Products:64-69-7

Detection of heavy metals

The meaning of heavy metals of this act is under the specified experimental condition, which can coloration effects with sodium sulfide or thioacetamide .The glasses of preparation or storage is not allowed to contain lead.

5.8.1 Reagents

a) Lead dinitrate:1μg/mL

b) Sodium hydroxide :10%(m/v)

c) Sodium sulfide :10%(m/v)

5.8.2 Preparation of lead standard solution

Weigh lead dinitrate 0.1599g ,relocated to 1000mL volumetric flask, plus nitric acid 5mL and water 50mL, diluted with water to the mark , shake, as the stock solution.

5.8.3 Determination of step

Before use, the exact amount of stock solution 1mL, relocated to a 100ml volumetric flask, dilute with water to the mark, shake, limit the use of the day .

Weigh sample 1g, after adding sodium hydroxide solution 5mL and 20mL of water to dissolve, set Nessler colorimetric tube, add 5 drops of sodium sulfide , shake , compared the color with 5mL lead standard solution after the same treatment, not deeper.

Determination of melting point

Instrument:

Micro melting point apparatus WRS-2A, Melting point tubes

Determination of step:

Open switch, stable 20min.

First set the starting temperature than the melting point of the low 10 ℃, heating rate 2 ℃ / min.

The sample was grind as fine as possible and load in a clean, dry melting point pipe ,until the sample was compressed into about 1cm high .When the actual temperature reaches the set temperature and stabilized . Inserted into the capillary with the sample, the simultaneous determination of three.

The determination of PH

Weigh a certain amount of samples into test tube, add a certain amount of water, shake and dissolve, determination of the pH used have been calibrated pH meter.

The determination of Loss on drying

Weigh a sample of approximately 2g (weighing accuracy 0.0001g),Record the weight of m,The sample was placed in a Petri dish constant weight (weight recorded as m0), the tile, the thickness of not more than 5mm, into the oven (As next dish cover removed) drying at 105-110 ℃ 3 hours.When removing, make sure the dish cover,be placed in a desiccator to cool, then weighed and the weight (including surface dish) m1.

Loss on drying in accordance with the following formula:

Where:

m-- sample, g

m0-- dish, g

m1-- After drying the quality of the sample and the dish, g