Posaconazole Intermediate CAS Number 184177-81-9

Name: Posaconazole Intermediate CAS Number 184177-81-9
Brand: Taizhou Volsen Chemical Co., Ltd.
Rating: 4.8 (20 reviews)

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Model No. :	184177-81-9
Brand Name :	VOLSENCHEM

10yrs

Taizhou, Zhejiang, China

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Product description

Posaconazole intermediate of [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester CAS number 184177-81-9. We used p-methoxyaniline with N, N (2-haloethyl) -4-nitroaniline as a starting material, in aprotic solvent, under basic conditions, after 5 steps to get it.
Although the route is longer, but the operation is simple, product quality is also very satisfactory. In general, we produce [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester 184177-81-9 instead of starting from the starting material because we are doing all intermediate of posaconazole Series, especially its N-1 step in biger production and inventory are very large, we usually use its previous step to directly synthesize the intermediates, which can greatly reduce the production time.

Thera. Category: Anti-fungal

Cas No.:184177-81-9

Synonym:CarbaMic acid, [4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-, phenyl ester (9CI);Posaconazole Impurity 14;PHENYL{4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE;[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester;

184177-81-9