Gastro-kinetic drugs Chemical Domperidone BP STANDARD
Gastro-kinetic drugs Chemical Domperidone BP STANDARD
Gastro-kinetic drugs Chemical Domperidone BP STANDARD
Gastro-kinetic drugs Chemical Domperidone BP STANDARD
Gastro-kinetic drugs Chemical Domperidone BP STANDARD
Gastro-kinetic drugs Chemical Domperidone BP STANDARD
Gastro-kinetic drugs Chemical Domperidone BP STANDARD

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Gastro-kinetic drugs Chemical Domperidone BP STANDARD

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Model No. : 57808-66-9
Brand Name : Jusheng
White Crystalline Powder : Medical Intermediate
8yrs

Wuhan, Hubei, China

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Product description

Domperidone Basic information

Gastro-kinetic drugs Chemical Properties Uses Production method
Product Name: Domperidone
Synonyms: 2h-benzimidazol-2-one,1,3-dihydro-5-chloro-1-(1-(3-(2,3-dihydro-2-oxo-1h-benzi;5-chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidaz;kw-5338;midazol-1-yl)propyl)-4-piperidinyl)-;
DOMPERIDONE;4-(5-chloro-2-oxo-1-benzimidazolinyl)-1-[3-(2-oxobenzimidazolinyl)propyl]piperidine;ALPHA-[2-(DIISOPROPYLAMINO)ETHYL]-ALPHA-PHENYL-2-PYRIDINE-ACETAMIDE;5-CHLORO-1-[1-[3-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)PROPYL]-4-PIPERIDINYL]-1,3-DIHYDRO-2H-BENZ-IMIDAZOL-2-ONE
CAS: 57808-66-9
MF: C22H24ClN5O2
MW: 425.91
EINECS: 260-968-7
Product Categories:Dopamine receptor;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labelled Compounds;VIOXX;Other APIs

Uses:
It is a kind of potent peripheral dopamine receptor antagonist with anti-vomiting and gastro-kinetic effects. 
It can affect the gastrointestinal motility to make the motility and tension of upper gastrointestinal tract return to normal and promote gastric emptying, 
enhancing the antral and duodenal motility, and coordinating the pyloric contraction. 
It can be used for the treatment of dyspepsia, and the nausea and vomiting induced by functional, organic, infection, dietary, radiation therapy or drug therapy. 
Because it almost has no inhibitory effect on dopamine receptor, there are no psychiatric and neurological side effects. And it can be used for treating the nausea caused by treating the Parkinson`s disease through taking dopamine agonists. 

It can be used as anticholinergic antispasmodics. 
Domperidone is a kind of phenyl imidazole compounds with a strong role in promoting gastric motility and antiemetic effect. It can strengthen the tension of the sphincter of the lower part of the esophagus, preventing the stomach - esophageal reflux, enhancing the gastric motility, 
promoting the gastric emptying, coordinating the stomach and duodenal motility, suppressing nausea, vomiting, and effectively preventing the bile reflux without affecting the secretion of gastric juice. 
This product is a kind of peripheral dopamine receptor antagonists which can directly block the gastrointestinal dopamine receptors and exhibit the stimulating effect of gastric motility. 
It can enhance the esophageal peristalsis and the tension of esophageal sphincter. Because of its poor penetration through the blood brain barrier, it has almost no antagonism against the dopamine receptor of the brain, 
and therefore can excluding the side effects of the spirit and the central nervous system.


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