Anti Immunosuppressant Rapamycin 53123-88-9

Name: Anti Immunosuppressant Rapamycin 53123-88-9
Brand: Taizhou Volsen Chemical Co., Ltd.
Rating: 4.0 (21 reviews)

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Model No. :	53123-88-9
Brand Name :	VOLSENCHEM
Function :	Antibiotic and Antimicrobial Agents

10yrs

Taizhou, Zhejiang, China

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Product description

Rapamycin (RAPA) is a novel macrolide immunosuppressive agent, It is white solid crystals, lipophilic, dissolved in methanol, ethanol, acetone, chloroform and other organic solvents. As early as the seventies of the 20th century, initially it was developed as as a low toxicity of antifungal drugs, in 1977, it was found with immunosuppressive effect, in 1989,Rapamycin began to use as a therapeutic organ transplant rejection of new drugs from the trial, from Animal experiments and the clinical application of the effect, is a good effect, low toxicity, no nephrotoxicity of the new immunosuppressive agents. now it is often used as a drug to maintain organ immune capacity (especially kidney transplantation) to slow the immune rejection after organ transplantation, but scientists have recently found another use which can be used to treat Alzheimer's disease (senile dementia ). What is interesting to them is that the main components of rapamycin also exist in the resurrection island of isolated bacteria in the soil, the latest experiments show that the application of the substance in the experimental mice can play a role in the recovery of cognitive deficiencies.
University of Chicago medical researchers use commercially available rapamycin oral tablets plus grapefruit juice treatment of melanoma (a European and American common malignancy disease), it can greatly improve the anti-cancer effect of other chemotherapy drugs, thereby extending the survival of patients time. Studies have shown that rapamycin is easily decomposed by enzymes after entering the digestive tract, whereas grapefruit juice contains a large amount of furanosalin, which inhibits the destruction of rapamycin by digestive enzymes , then improve the bioavailability of rapamycin. It is said that the earliest Dutch doctors have found that grapefruit juice has the effect of improving the oral absorption of mountain Ming, the European and American doctors apply it to the rapamycin preparations.

Thera. Category:Anti Immunosuppressant

Cas No.:53123-88-9

Synonyms: RAPAMYCIN, STREPTOMYCES HYGROSCOPICUS;RPM;AY 22989;23,27-EPOXY-3H-PYRIDO(2,1-C)(1,4)OXAAZACYCLOHENTRIACONTINE;NSC-226080;RAPA;RAPAMUNE;RAPAMYCIN;

53123-88-9