1 / 1
Model No. : | 123855-55-0 |
---|---|
Brand Name : | VOLSENCHEM |
Taizhou, Zhejiang, China
Product description
In a large number of synthetic lafutidine patent introduction, Lafutidine intermediates 3 CAS number 123855-55-0 is often synthesized as an active ester intermediate with the corresponding intermediate,take condensation reaction to synthesis lafutidine. The general procedure is as following: use (Z) -2 - ((4-bromobut-2-en-1-yl) oxy) -4- (piperidin-1-ylmethyl) pyridine as raw material to add phthalimide Potassium salt,subjected to a two-step reaction to give intermediate primary amine, primary amine and lafutidine intermediate 3 by condensation to give lafutidine. At present, most manufacturers use this method to synthesis, but this method has obvious shortcomings, the purity of primary amine is too low, and ultimately affect the purity of raw materials. There are few reports about the synthesis of lafutidine intermediate 3 CAS number 123855-55-0, which is only a simple role as an active ester in the amidation reaction, and there is no more in-depth introduction. Specific synthesis methods still need R & D persons to develop according to their own synthesis theory and experience.
Thera. Category:Antiulcerative
Cas No.:123855-55-0
Synonym:p-nitrophenyl 2-(furfurylsulfinyl)acetate;(FURAN-2-YL-METHANESULFINYL) ACETIC ACID 4-NITROPHENYL ESTER;4-NITROPHENYL 2-(FURAN-2-YL-METHYLSULFINYL)ACETATE;4-nitrophenyl 2-(furfurylsulfinyl)acetic acid;
Molecular Formula:C13H11NO6S
Molecular Weight:309.29
Pharmacopeia: In house Spec.
Specifications:Available on request
Packing:Export worthy packing
Material Safety Data Sheet:Available on request
Usage :Intermediates for Lafutifine
Competitive Advantage: Good quality and favorable price
Related intermediate of Lafutidine
1) 4-Nitrophenyl 2-(furfurylsulfinyl)acetic acid CAS 123855-55-0)
2) N-{4-[4-(Piperidinomethyl)pyridyl-2-oxy]-cis-2-butene}phthalimide maleic acid CAS 146447-26-9
3) 2-Chloroisonicotinic acid CAS 6313-54-8
Taizhou, Zhejiang, China
Send your inquiry to this supplier