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4-Iodo-1-chloro-2-(4-ethoxybenzyl)benzene For Ertugliflozin 1103738-29-9

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4-Iodo-1-chloro-2-(4-ethoxybenzyl)benzene For Ertugliflozin 1103738-29-9

Name: 4-Iodo-1-chloro-2-(4-ethoxybenzyl)benzene For Ertugliflozin 1103738-29-9
Brand: Taizhou Volsen Chemical Co., Ltd.
Rating: 4.5 (3 reviews)

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Model No. :	1103738-29-9
Brand Name :	VOLSENCHEM

10yrs

Taizhou, Zhejiang, China

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Product description

Ertugliflozin intermediate 3 has the cas number of 1103738-29-9, molecular formula of C15H14ClIO, Molecular weight 372.62853, according the related literature reported synthesis method is as follows,use 3-Carboxy-4-chlorotoluene and aphenoxyethane as raw materials to obtain the first product Acetaldehyde compound.Then obtain acetaldehyde (5-Iodo-2-chlorophenyl) (4-ethoxyphenyl) methanone by adding AIBN, CCl4, reflux, 1-iodo-5-pyrrolidinedione and the like,later adding BF3, Et2O, Et3SiH, DCM and MeCN to obtain the target product of Ertugliflozin intermediate 3 cas 1103738-29-9,after experimental verification and calculation, we found that the comprehensive cost of this route is relatively high, so need to break the existing thinking mode, standing in a new perspective to design its route. Our R & D team almost gave up the weekend and the national statutory holiday in nearly six months,, threw themselves into the product development, they pay a great effort to this project.

Thera. Category: Anti-diabetes

Cas No.: 1103738-29-9

Synonym:Benzene, 1-chloro-2-[(4-ethoxyphenyl)Methyl]-4-iodo-; 4-Iodo-1-chloro-2-(4-ethoxybenzyl)benzene;1-chloro-2-(4-ethoxybenzyl)-4-iodobenzene;1-Chloro-2-[(4-ethoxyphenyl)Methyl]-4-iodobenzene;

Molecular Formula:C15H14ClIO